Research Programs

A researcher at Penn State Children’s Hospital talks to a participant in a clinical study.

From cutting-edge basic research, Penn State Children’s Hospital engages in research aimed at understanding, treating, and ultimately eliminating childhood disease.

A Penn State researcher helps a clinical trial patient.

Find a clinical trial

See pediatric research studies that are currently recruiting participants.

Search our active trials.

Contact the Pediatric Clinical Research Office

Research at the Children’s Hospital includes basic science and clinical investigation in a wide spectrum of pediatric fields and involves the University Park campus. This research aims to reduce morbidity and increase the success of treatment of many childhood diseases.

For more information, call 717-531-5656.

Additional programs

Pediatric cancer research programs

The laboratory of Barbara A. Miller, MD, chief of the Division of Pediatric Hematology/Oncology, focuses on the role of ion channels in cell proliferation and differentiation and in carcinogenesis. Dr. Miller's laboratory is studying the function of members of the TRP super family of cation channels in malignant cell proliferation in leukemia, lymphoma, and neuroblastoma.

The laboratory of Sinisa Dovat, MD, PhD, director of translational research for both the Four Diamonds Pediatric Cancer Research Center and the Pediatric Oncology Experimental Therapeutics Program, aims to understand basic mechanisms of disease in order to integrate the latest research achievements into clinical practice. His research focuses on biology and treatment of leukemia; molecular mechanisms of cellular immortalization and senescence; and accelerated drug discovery.

Pediatric cardiovascular research

The goal of the Center for Pediatric Cardiovascular Research is to minimize the negative effects of cardiovascular operations and cardiopulmonary bypass in neonates, infants, and children through the development of novel technologies and methodologies. Researchers focus particularly on reducing the associated morbidity of cerebral, myocardial, pulmonary, and renal injury.